Controllable DNA condensation through cucurbit[6]uril in 2D pseudopolyrotaxanes.
نویسندگان
چکیده
2D pseudopolyrotaxanes containing beta-cyclodextrins and cucurbit[6]urils can induce DNA condensation, and the number of cucurbit[6]urils threaded onto the side chains of beta-cyclodextrins plays important roles in this process.
منابع مشابه
Formation of dynamic aggregates in water by cucurbit[5]uril capped with gold nanoparticles.
Supramolecular capping of cucurbit[5]uril (CB[5]) by gold nanoparticles has been achieved via a facile reduction of an aqueous solution of HAuCl(4) by NaBH(4) in the presence of various amounts of CB[5]. The resultant assemblies were very stable in solution, and were found to form dynamic aggregates consisting of a controllable ratio of singly and doubly capped CB[5].
متن کاملTopical Cream-Based Dosage Forms of the Macrocyclic Drug Delivery Vehicle Cucurbit[6]uril
The macrocycle family of molecules called cucurbit[n]urils are potential drug delivery vehicles as they are able to form host-guest complexes with many different classes of drugs. This study aimed to examine the utility of Cucurbit[6]uril (CB[6]) in topical cream-based formulations for either localised treatment or for transdermal delivery. Cucurbit[6]uril was formulated into both buffered crea...
متن کاملIonic liquids as novel guests for cucurbit[6]uril in neutral water.
Cucurbit[6]uril was dissolved through encapsulation of an imidazolium-based ionic liquid guest in a pure water environment and the dissolution ability could be tuned by augmenting the imidazolium structure.
متن کاملSupramolecular assemblies built with host-stabilized charge-transfer interactions.
Host-stabilized charge-transfer (CT) interactions and supramolecular assemblies built with these interactions are described. A variety of supramolecular assemblies including polyrotaxanes, molecular necklaces, and rotaxane dendrimers were synthesized through the intramolecular or intermolecular host-stabilized CT complex formation using cucurbit[8]uril (CB[8]) and D-A molecules having both elec...
متن کاملCucurbit[6]uril is an ultrasensitive (129)Xe NMR contrast agent.
A lack of molecular contrast agents has slowed the application of ultrasensitive hyperpolarized (129)Xe NMR methods. Here, we report that commercially available cucurbit[6]uril (CB[6]) undergoes rapid xenon exchange kinetics at 300 K, and is detectable by Hyper-CEST NMR at 1.8 pM in PBS and at 1 μM in human plasma where many molecules, including polyamines, can compete with xenon for CB[6] bind...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 32 شماره
صفحات -
تاریخ انتشار 2007